Synovial Fluid Changes in Intra-articular Therapy
نویسندگان
چکیده
منابع مشابه
Serial studies of synovial fluid in evaluating intra-articular agents.
One of the most difficult problems in the study of rheumatic diseases is the evaluation of an antiinflammatory response. That this is true in intraarticular as well as systemic therapy is illustrated by the divergence of results reported in the literature. For example, Cohen and others (1954) concluded, by purely clinical evaluation in a large number of patients, that cortisone acetate was equa...
متن کاملImportance of synovial fluid aspiration when injecting intra-articular corticosteroids.
OBJECTIVE The aim of this prospective study was to find if a complete synovial fluid aspiration before injecting intra-articular corticosteroids influences the treatment result. METHODS The study was performed in 147 patients with rheumatoid arthritis (RA). One hundred and ninety one knees with synovitis were randomised to arthrocentesis (n=95) or no arthrocentesis (n = 96) before 20 mg triam...
متن کاملChanges in concentrations of haemostatic and inflammatory biomarkers in synovial fluid after intra-articular injection of lipopolysaccharide in horses
BACKGROUND Septic arthritis is a common and potentially devastating disease characterized by severe intra-articular (IA) inflammation and fibrin deposition. Research into equine joint pathologies has focused on inflammation, but recent research in humans suggests that both haemostatic and inflammatory pathways are activated in the joint compartment in arthritic conditions. The aim of this study...
متن کاملChanges in synovial fluid biomarkers and clinical efficacy of intra-articular injections of hyaluronic acid for patients with knee osteoarthritis
BACKGROUND The changes in synovial fluid biomarkers after intra-articular injection of hyarulonic acid (IA HA) remain controversial. We investigate the changes in the properties of synovial fluid (SF) and clinical symptoms before the first and fifth IA HA. METHODS A total of 73 patients (73 knees) with symptomatic knee osteoarthritis were treated with five weekly intra-articular injections of...
متن کاملEffects of intra-articular corticosteroids in vivo on synovial fluid variables in rheumatoid synovitis.
Intra-articular instillation of corticosteroids in patients with rheumatoid arthritis (RA) is often followed by transient relief of symptoms and signs of local synovitis (Hollander, Brown, Jessar, and Brown, 1951; Ziff, Scull, Ford, McEwen, and Bunim, 1952). The basis for this clinical improvement is not known and has not been comprehensively correlated with changes in the characteristic synovi...
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ژورنال
عنوان ژورنال: BMJ
سال: 1959
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5132.1271